Determination of antibodies to neutrophil cytoplasm (ANCA) in blood. Prices, reviews, ratings

• General information
• Procedure
• Indications
• Contraindications
• Prices and clinics

General information

Anti-neutrophil cytoplasm antibodies are a group of antibodies formed against various proteins/enzymes of the cytoplasm of neutrophils and monocytes. It was found that a number of enzymes contained in azurophilic granules of neutrophils act as ANCA antigens. These specific cells are formed when the patient's body has a number of systemic diseases that affect connective tissue. Most often, we are talking about vasculitis.

Procedure

Preparation

This type of diagnostic procedure is one of the most frequently used in modern medical practice. No restrictions are required in diet or nutrition.

Procedure for determining antibodies to neutrophil cytoplasm (ANCA) in the blood

Using a special device, the doctor makes a careful puncture of the vein, having previously treated the affected area with an antiseptic. After this, fluid is collected. After venipuncture, blood is collected in an empty tube or with a separating gel to obtain serum.

Rehabilitation period

You only need to apply an antiseptic and stop the bleeding. A minor vein is taken, so there is no need to worry about the risk of severe blood loss.

If a hematoma forms at the site of venipuncture, warming compresses are prescribed.

Indications

The main indication is suspicion of diseases called vasculitis. This is a whole series of diseases that have similar symptoms, affecting the connective tissue of the patient's body.

Contraindications

Poor coagulation is the only significant contraindication to manipulations.

Decoding the analysis

Reference values: titer

The ANCA definition is suitable for assessing the results of treatment. In the remission phase, antibodies are often not detected. Increased norm:

• Vasculitis associated with antibodies to neutrophil cytoplasm - Wegener's granulomatosis, microscopic polyangiitis, nodular periarteritis, Churg-Strauss syndrome.
• Vasculitis in rheumatoid arthritis.
• Vasculitis in systemic lupus erythematosus.
• Chronic hepatitis.
• Crohn's disease (in 10% - 20% of cases).
• Ulcerative colitis 50% - 90% of cases).

Prices and clinics

The service is provided in private and public clinics by rheumatologists. You can find out more detailed information on the medical portal .