Blood Renin Determination. Prices, Reviews, Ratings
General information
The renin element is a proteolytic enzyme that affects blood pressure and water-salt homeostasis. In addition, the products of its synthesis and decay regulate the metabolism of sodium and potassium.
Some forms of enzymes are formed in specific cells that work in the kidneys, and its formation is restored when the blood flow in the renal-arterial environment decreases.
Procedure
Preparation
Preparation for such an action requires being in a horizontal position at complete rest for an hour. The material itself is taken only on an empty stomach, but a small amount of water is allowed. Alcohol should not be consumed for 24 hours, and strong nervous, physical and emotional overexcitement is also prohibited.
3-4 weeks before, the need to cancel the medications taken that can affect the incoming data (diuretics, oral contraceptives, regulators) is separately agreed upon. Such drugs include, in particular, captopril, diazoxide, nitroprusside, enalapril, chlorpropamide, guanethidine, lisinopril and many others.
The procedure for determining renin in the blood
Defining the volume of a substance (renin analysis) takes a couple of hours and allows you to do without the use of anesthesia. For the experiment, you will need only a few milliliters of human venous blood. At the output, the concentration of coagulant in plasma (μIU / ml) is diagnosed.
The venous method is used to detect enzyme activity.
Blood is collected in test tubes (pre-cooled) and immediately placed in a glass of ice. If there is no equipped laboratory, then they are carefully transported and transferred to another clinic. Experts advise to give preference to those institutions for research that do not require transportation.
A set of additional studies is recommended in consultation with the doctor. After the session, discomfort that arose during the collection of material may persist.
Indications
The technique is recommended for those who want to:
- determine the level of pressure or primary and secondary hyperaldosteronism;
- find out an option for increasing the effectiveness of antihypertensive therapy;
- detect tumors.
Decoding the analysis
Treatment cannot be based only on this test. The interpretation of the results is divided into two categories. In case of increased content, there is a possibility of such diseases as hypertension, heart failure, liver cirrhosis, hepatitis, Bartter syndrome, adrenocortical insufficiency. If it is decreased, this indicates the presence of Liddle syndrome, primary hyperaldosteronism, parenchymatous kidney disease.
Prices and clinics
A blood test for renin is performed by an endocrinologist in a clinic or medical center. You can find out more detailed information on the medical portal .
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