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Medical dictionary » Tests » HSV-1/2 IgM (Class M Antibodies to Herpes Simplex Virus). Prices, Reviews, Ratings

HSV-1/2 IgM (Class M Antibodies to Herpes Simplex Virus). Prices, Reviews, Ratings

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HSV-1 and HSV-2 are related forms of the herpes virus that manifest as rashes on mucous membranes (lips, genitals). Herpes caused by the first type is localized on the outer and inner lip surfaces but can affect other mucous membranes in advanced stages. The second form causes vesicles exclusively on the genitals.

HSV-1 and HSV-2 are related forms of the herpes virus that manifest as rashes on mucous membranes (lips, genitals). Herpes caused by the first type is localized on the outer and inner lip surfaces but can affect other mucous membranes in advanced stages. The second form causes vesicles exclusively on the genitals.

General Information

The disease is sexually transmitted. Both viruses remain in the human body permanently, shifting from latent to active states, manifesting as rashes. This is termed manifest expression, resulting from reduced immunity due to various factors. Primary infection can occur in early childhood.

HSV-1 is associated with wet, small blisters on the lips and, with severe immune suppression, can affect internal organs. HSV-2 primarily localizes on external genitalia. Without treatment, rashes may resolve in weeks but recur within 5-10 days. Additional symptoms include itching, pain, vesicle formation, and later ulcers or erosions.

In pregnant women, the virus crosses the placenta into the fetal bloodstream, posing risks of fetal abnormalities, pregnancy loss, miscarriage, or preterm birth. Statistics show 50% of infected children later exhibit developmental delays and vision organ pathologies.

Upon herpes virus entry, the body produces specific IgM-class immunoglobulins, detectable by day 4-5 post-infection, peaking at two-three weeks. IgM antibodies are the primary marker for this condition.

A positive IgM blood test indicates acute herpes infection, less commonly reactivation of chronic pathology. A negative result suggests no infection, early infection (within two days), or chronic progression.

Indications for HSV-1/2 IgM Testing

Testing may be ordered by an obstetrician-gynecologist, urologist, dermatovenereologist, immunologist, or andrologist. It’s indicated for pregnancy planning (both partners), initial infection signs (itching, mucosal redness), post-unprotected contact with an infected person, differential infection diagnosis, and in pregnant women with fetoplacental insufficiency or intrauterine infection signs.

HSV-1/2 IgM blood testing is mandatory for immunocompromised individuals and HIV patients.

How HSV-1/2 IgM Testing Is Conducted

Venous blood is drawn. To avoid skewed results, follow these guidelines:

  • Stop medications 10-15 days prior; if unavoidable, inform the lab technician of drug names and dosages for documentation.
  • Test on an empty stomach, with over 8 hours since the last meal.
  • Avoid juice, tea, coffee; drink only plain water.
  • No physical exercise or stress 15-30 minutes beforehand.

The patient sits in a chair or on a couch, placing their arm on a flat surface. A tourniquet is applied 7-10 cm above the puncture site. After 20-30 seconds, blood is drawn via syringe, and the site is treated with alcohol and sealed with sterile plaster.

Turnaround Time for HSV-1/2 IgM Testing

Results are ready 3-5 days post-sample submission.

Prices and Clinics

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27 Jan 2024, 13:49
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