Chlamydia IgM (Chlamydia trachomatis). Prices, Reviews, Ratings
Chlamydia, caused by the pathogenic bacteria Chlamydia trachomatis (CT), is an invasive disease affecting men and women.
Chlamydia, caused by the pathogenic bacteria Chlamydia trachomatis (CT), is an invasive disease affecting men and women.
Infection typically occurs via sexual contact with an infected partner. Chlamydial bacteria cause urogenital diseases, certain arthritides, trachoma, conjunctivitis, and neonatal pneumonia, exerting virulent (affecting vascular endothelium, lymph nodes, lung tissue, conjunctiva, and genital mucosa) and toxigenic (releasing endotoxins causing bleeding) effects. As a protective response, the body sensitizes immunocompetent cells, producing antibodies (Abs) of various classes (IgM, IgA, IgG).
Indications for Chlamydia IgM Testing
Changes in cellular and humoral immune factors during Chlamydia invasion stimulate production of multiple immunoglobulins against CT antigens.
IgM presence signals potential infection, detectable in blood by day 5 post-infection. In serological tests, it indicates an acute pathogenesis phase, peaking at days 7–14, then declining and disappearing within 2–3 months.
IgM detection, with production dynamics in blood serum, serves as an additional pathogen marker and staging tool.
How Is Chlamydia IgM Testing Conducted?
Anti-chlamydial IgM detection uses test systems with ELISA, IIF, and IHA methods.
A specialist draws venous blood, and serum is obtained by centrifugation. Testing stages:
- Incubation-1: Patient serum is mixed with sensitized Chlamydia antigen and held at a set temperature to bind with CT antibodies (forming an Ag-Ab complex).
- Washing-1: Removal of unbound non-specific globulins.
- Incubation-2: The Ag-Ab complex is thermostated with enzyme-labeled anti-IgM serum.
- Washing-2: Removal of unbound labeled antibodies.
- Enzymatic reaction produces a colored product, its intensity reflecting specific IgM antibody complex levels in the test mixture and patient sample.
Some methods slightly adjust serological techniques, but the identification principle remains.
IgM titer ranges for Chlamydia trachomatis stages: initial (acute) – 50–3200, chronic – 55–200, reinfection – <50, post-recovery – ≤50.
Completion Time for Chlamydia IgM Testing
Results are ready in 90–210 minutes.
Prices and Clinics
Result speed depends on specific test systems and lab analyzers. Find details on diagnostic centers offering this service on the medical portal, and book appointments online or by phone.
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