Chlamydia IgG (Chlamydia trachomatis). Prices, Reviews, Ratings
Chlamydia is a disease caused by the pathogenic bacteria Chlamydia trachomatis (CT). The primary transmission route is sexual contact with an infected person. During parasitism, chlamydia exerts virulent (affecting lymph nodes, genital mucosa, lung tissue, vascular endothelium) and toxigenic (releasing endotoxins that stimulate bleeding) effects.
Chlamydia is a disease caused by the pathogenic bacteria Chlamydia trachomatis (CT). The primary transmission route is sexual contact with an infected person. During parasitism, chlamydia exerts virulent (affecting lymph nodes, genital mucosa, lung tissue, vascular endothelium) and toxigenic (releasing endotoxins that stimulate bleeding) effects. Their intracellular parasitism in the host causes numerous urogenital tract diseases, certain arthritides, conjunctivitis, trachoma, and neonatal pneumonia. With antigenic properties, they trigger antibody (Ab) sensitization of various classes (IgM, IgA, IgG).
Indications for Chlamydia IgG Testing
Activation of cellular and humoral immune responses during chlamydial invasion stimulates production of multiple immunoglobulin types against Chlamydia antigens. A key indicator of immune response is IgG production.
Diagnostically significant IgG levels in blood serum appear by days 13–15 post-infection, rising over 20–28 days. Its presence confirms a positive immune response in current, chronic, or past infections. Post-treatment, low levels may persist for years.
High IgG levels are particularly useful for chronic and systemic conditions like perihepatitis, epididymitis, Reiter’s syndrome, pneumonia, and salpingitis, and for monitoring recovery from complications of ascending CT infections.
How Is Chlamydia IgG Testing Conducted?
Anti-chlamydial IgG detection uses test systems and serological methods: enzyme-linked immunosorbent assay (ELISA), indirect immunofluorescence (IIF), and indirect hemagglutination (IHA).
A specialist draws venous blood, and serum is obtained by centrifuging the sample. Testing stages include:
- Incubation-1: Patient serum is mixed with purified Chlamydia antigen on a plate and held at a set temperature to bind with CT antibodies (forming an Ag-Ab complex).
- Washing-1: Removal of unbound non-specific globulins.
- Incubation-2: The Ag-Ab complex is thermostated with enzyme-labeled anti-IgG serum.
- Washing-2: Removal of unbound labeled antibodies.
- Enzymatic reaction produces a colored product, its intensity reflecting specific IgG antibody complex levels in the test mixture and patient sample.
Fluorescence and agglutination detection have minor technical variations but retain the same identification principle.
IgG titer ranges for Chlamydia trachomatis stages: initial (acute) – 100–6400, chronic – 105–1600, reinfection – 105–51200, post-recovery – 100–400.
Completion Time for Chlamydia IgG Testing
In equipped labs with trained staff, testing is efficient, with results available 90–210 minutes post-blood collection.
Prices and Clinics
Effective, reliable testing is crucial for successful Chlamydia treatment. Trust certified diagnostic centers. Choose the best center on the medical portal.
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