Total IgM. Prices, Reviews, Ratings
Total IgM – a humoral immunity component. During acute inflammation, class M antibody production surges, entering blood vessels for primary defense.
Total IgM – a humoral immunity component. During acute inflammation, class M antibody production surges, entering blood vessels for primary defense.
General Information
Low IgM levels suggest humoral immunity deficiency. Chronic viral infections or exhaustive states reduce IgM.
Elevated levels indicate acute infections from various microorganisms.
IgM also rises in autoimmune disorders like systemic lupus erythematosus, autoimmune thyroiditis, rheumatoid arthritis (with rheumatoid factor), pyelonephritis, and myeloma.
IgM is produced in plasma cells, comprising 5-10% of a healthy body’s immunoglobulins. As macroglobulins, their large mass prevents tissue transport.
IgM binds complement, agglutinates bacteria, and destroys viruses.
Their key role is enhancing phagocytosis to eliminate foreign microbes from the bloodstream.
IgM includes isohemagglutinins, cold agglutinins, and rheumatoid factor.
Indications for Total IgM Testing
Testing is indicated for:
- Recurrent infections, chronic inflammation, including severe cases;
- Intrauterine infection (cord blood sampling);
- Autoimmune diseases, including rheumatoid arthritis;
- Oncological conditions;
- Liver dysfunctions: hepatitis, cirrhosis;
- Excess macroglobulin production (evaluating Waldenström syndrome therapy).
How Total IgM Testing Is Performed
Serum from venous blood determines antibody concentration. Avoid morning and evening meals, smoking, and alcohol prior to testing.
Processing Time for Total IgM Testing
Results are ready within 4 hours.
Prices and Clinics
Learn more about diagnostic centers offering this service on the medical portal.
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