Total IgA. Prices, Reviews, Ratings
Total IgA – a component of humoral immunity. These proteins protect against foreign agents locally (in tonsils, adenoids, intestines, etc.) and are present in blood serum, saliva, intestinal and respiratory secretions, breast milk, and tears.
Total IgA – a component of humoral immunity. These proteins protect against foreign agents locally (in tonsils, adenoids, intestines, etc.) and are present in blood serum, saliva, intestinal and respiratory secretions, breast milk, and tears.
General Information
Class A immunoglobulins work with nonspecific immune components to maintain mucosal health. They bind to microbial and viral cells, preventing adhesion to body tissues.
Low levels indicate weakened systemic and organ-specific immunity or ongoing viral inflammation.
Elevated levels suggest:
- Acute or chronic infections from bacteria, fungi, or parasites;
- Liver pathologies;
- Autoimmune processes (e.g., systemic lupus erythematosus).
Class A comprises up to 15% of soluble immunoglobulins. In serum, monomeric molecules are detected. IgA functions concentrate on mucosal surfaces and fluid tissues, with a secretory component preserving its properties post-digestive enzyme exposure.
Indications for Total IgA Testing
Main reasons include local immune responses, acute/chronic infections, and liver/kidney dysfunctions.
It’s recommended for:
- Chronic hepatitis, severe liver damage;
- Frequent respiratory issues (sinusitis, otitis, tonsillitis, asthma), meningitis;
- Persistent diarrhea, malabsorption;
- Ataxia-telangiectasia;
- Lymphatic cancers (leukemias, lymphomas, myelomas, reticulosarcomas);
- Autoimmune issues: rheumatoid arthritis, SLE, dermatomyositis;
- Anaphylactic reactions post-transfusion.
How Total IgA Testing Is Performed
Venous blood is drawn on an empty stomach. A light dinner is allowed the evening prior, but avoid alcohol and smoking hours before.
With low levels, prevent infection and monitor health post-collection.
With elevated levels, report bone pain, spontaneous fractures, high calcium, or renal insufficiency signs to the doctor immediately.
Processing Time for Total IgA Testing
Determining total IgA takes about 4 hours.
Prices and Clinics
More details on clinics offering this service are available on the medical portal.
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