HSV-1/2 IgG (Class G Antibodies to Herpes Simplex Virus). Prices, Reviews, Ratings
The most common herpes form is genital, caused by HSV-1 and HSV-2 viruses.
The most common herpes form is genital, caused by HSV-1 and HSV-2 viruses.
General Information
HSV-1 manifests on the face, spreading to genitals with weakened immunity. HSV-2 localizes solely on genitals – penile head in men, labia in women, extending to the vagina and perianal area in advanced cases.
Transmission occurs via:
- Sexual contact;
- Prolonged contact of infected mucosa with healthy mucosa;
- Mother-to-child during pregnancy, childbirth, or breastfeeding.
HSV-1 commonly affects preschool children, with high infection risk up to age 5, decreasing with age. The main symptom is a cold sore, typically in one spot, shifting to the mouth, eye mucosa, or genitals with severe immunity decline or advanced stages.
HSV-2 appears as numerous tiny fluid-filled vesicles on genitals, bursting and drying within 1-2 weeks, then vanishing, only to recur later. The virus embeds in sacral spinal nerve fibers, reactivating with minor immunity drops.
HSV-1/2 increases HIV susceptibility and causes cervical/vaginal cancer.
In pregnant women, it crosses the placenta, impairing fetal mental/physical development, leading to brain damage, disproportionate growth, and vision/hearing issues in children.
High mortality rates occur in infected newborns, alongside frequent stillbirths and fetoplacental insufficiency. Infections during childbirth or via breast milk are common.
The body responds with IgM immunoglobulins detectable 1-5 days post-infection, peaking by day 15, converting to IgG, with IgM lingering 30-60 days post-treatment and IgG persisting lifelong, causing recurrent herpes in chronic cases.
Positive HSV-1/2 IgG blood test results indicate chronic infection with low intrauterine infection risk; negative results rule out chronic disease but not acute (IgM) infection.
Indications for HSV-1/2 IgG Testing
Ordered by dermatovenereologists, gynecologists, urologists, or immunologists for:
- Recurrent herpes (>1/month);
- Persistent symptoms: rash, vesicles, itching, pain, ulcers, slow-healing erosions;
- Pregnancy planning (both partners);
- Fetoplacental insufficiency/intrauterine infection signs in the second trimester;
- Immunity decline.
How HSV-1/2 IgG Testing Is Conducted
Venous blood is drawn with recommendations:
- Stop medications two weeks prior; if not, note drug names/doses in lab referral;
- Test mornings on an empty stomach (last meal 6-8 hours prior);
- Plain water only; no sugary drinks, tea, coffee, juice;
- Avoid physical exertion.
Turnaround Time for HSV-1/2 IgG Testing
Lab analysis takes 3-5 days.
Prices and Clinics
Select a diagnostic center offering this service via the website.
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