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CMV IgG Avidity. Prices, Reviews, Ratings

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The CMV IgG avidity test determines the stages and forms of cytomegalovirus in the body. Avidity is the binding strength between viral infection components and their antibodies.

The CMV IgG avidity test determines the stages and forms of cytomegalovirus in the body. Avidity is the binding strength between viral infection components and their antibodies.

General Information

The immune response to viral infection grows gradually, engaging more immune system components over time. By measuring each component’s activity, specialists can gauge infection intensity.

Initially, macrophages degrade viral particles, presenting antigens on their surfaces, stimulating lymphocytes to produce antibodies—immunoglobulins.

Immunoglobulins are key in controlling viral replication. Determining their levels, especially IgM and IgG, is a critical diagnostic step.

IgG immunoglobulin structure, with only two antigen-binding sites compared to IgM’s ten, affects avidity. Despite IgM’s higher avidity, its short circulation time makes IgG the preferred diagnostic target.

IgG antibodies appear in the blood about a month post-infection, peaking rapidly, then stabilizing lifelong, with reactivation boosting their levels.

Indications for CMV IgG Avidity Testing

Testing is crucial during pregnancy or planning, if ultrasound reveals fetal anomalies, and for immunocompromised individuals (e.g., HIV-positive).

How CMV IgG Avidity Test Is Conducted

A specialist draws venous blood.

No special preparation is needed. Finish eating hours before, avoid fried/fatty foods and alcohol, and refrain from smoking or overexertion.

Completion Time for CMV IgG Avidity Test

Results processing typically takes no more than one business day.

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27 Jan 2025, 09:53
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