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Measles IgG (Class G Antibodies to Measles). Prices, Reviews, Ratings

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The IgG particle consists of RNA, a protein capsid, and a lipid envelope.

The IgG particle consists of RNA, a protein capsid, and a lipid envelope.

General Information

The measles virus belongs to the paramyxovirus class. Children aged 1-10 are most affected, though widespread vaccination has reduced this rate. The primary transmission route is airborne.

Upon entering the mucosal environment (nasal and oral cavities), the bacterium multiplies. It spreads via blood to the lymph, infecting all organ systems. Patients experience:

  • Runny nose;
  • Dry cough;
  • Fever of 38-39°C;
  • Red eyes, purulent discharge, or conjunctivitis;
  • Diarrhea, vomiting, abdominal pain;
  • Characteristic full-body rash.

This is the virus’s active phase, when the patient is most contagious. Simultaneously, IgG antibodies appear in the blood, increasing with the immune response. Post-measles, these antibodies persist lifelong. Newborns may have transplacentally acquired IgG, preventing clinical symptoms or transmission. After 6 months, immunity wanes, increasing infection risk.

The disease can cause complications like respiratory tract invasion, otitis, pneumonia, and panencephalitis.

In infected pregnant women, it may lead to premature birth, stillbirth, or intrauterine fetal death.

A therapist, gynecologist, or infectious disease specialist orders the lab test. If no IgG antibodies are detected in the serum, urgent vaccination is required.

Indications for Testing

Diagnosis is necessary for:

  • First-trimester pregnancy screenings;
  • Unexplained rashes;
  • Pre-vaccination testing;
  • Suspected intrauterine infections;
  • Epidemiological studies.

Biochemical reactions detect G-class antibodies produced solely against the Polinosa morbillarum pathogen. A nonspecific measles sign is leukopenia (low neutrophil and lymphocyte counts during the rash period).

How Measles IgG Testing Is Conducted

A therapist or geneticist orders the test. Blood is drawn in the morning, with the last meal 8-10 hours prior. Drinking is allowed. Medications and multivitamins may skew results; inform the doctor if unavoidable. Limit exertion, nicotine, alcohol, and fatty foods for 24 hours.

Result interpretation:

  • Positive – above 0.18 IU/mL.
  • Negative – below 1.12 IU/mL.
  • Doubtful – 0.13-0.17 IU/mL, the “gray zone.” Retesting is required after two weeks.

Turnaround Time for Measles IgG Testing

Results are ready within 2-3 working days.

Prices and Clinics

Choose a diagnostic center and book an appointment or consultation via the medical information portal.

21 Feb 2024, 17:01
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