Leukocyte Differential. Prices, Reviews, Ratings
Human blood contains white blood cells – leukocytes – crucial for protective and restorative processes. They are divided into granular and agranular groups. The ratio of different white blood cell types in a sample, expressed as percentages, is called the leukocyte differential.
Human blood contains white blood cells – leukocytes – crucial for protective and restorative processes. They are divided into granular and agranular groups. The ratio of different white blood cell types in a sample, expressed as percentages, is called the leukocyte differential.
Indications for Leukocyte Differential Testing
The differential characteristically changes physiologically and with various infectious and parasitic conditions, making its calculation and interpretation significant.
Elevated levels (leukocytosis) occur with inflammation and infections, with a left shift toward young neutrophil forms (myelocytes, juveniles, band neutrophils), indicating disease severity. Increased leukocyte counts without a left shift happen in physiological states like post-exercise, emotional stress, pain, or pregnancy, with cells exiting bone marrow and spleen lymph nodes.
Reduced levels (leukopenia) are often linked to technological progress, radiation exposure, radiation sickness, autoimmune disorders, malignancies, and bone marrow damage.
This test is part of an extended complete blood count, ordered during initial exams, routine, and dispensary evaluations. It aids differential diagnosis of various etiologies and monitors therapy effectiveness.
How Leukocyte Differential Counting Is Conducted
Venous or capillary blood stabilized with ethylenediaminetetraacetic acid (EDTA) is used. Lab techniques involve sample collection and preparation, considering cell volume and shape.
Leukogram analysis on a hematology analyzer is combined with manual microscopic biomaterial review.
Common counting methods include studying stained smears, Goryaev chamber counts, and hematology analyzers.
Leukocyte differentiation registers visible configurations by group, requiring specialized skills for accurate distribution and recognition.
Normal differential values:
- Lymphocytes (LYM) – 18-45%.
- Neutrophils (NEUT) – 45-74%, with band neutrophils 0-4%, segmented 45-70%.
- Eosinophils (EOS) – 0-7%.
- Monocytes (MON) – 4-10%.
- Basophils (BAS) – 0-2%.
- Absolute counts (×10⁹/L) – lymphocytes (LYMabs) – 1.2-3.5, granulocytes (GRANabs) – 1.4-6.6, neutrophils (NEUTabs) – 1.3-6.7, eosinophils (EOSabs) – 0.0-0.3.
Turnaround Time for Leukocyte Differential Counting
Latest-generation analyzers prepare smears, provide full differentials, report counts, note pathological cell forms, and display images, taking 1-5 minutes.
Prices and Clinics
Top diagnostic centers with cutting-edge equipment ensure accuracy and speed. Use the medical portal to find a clinic offering this service, access information, and get free online appointment registration assistance.
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