Schistosomiasis Test. Prices, Reviews, Ratings
Schistosomiasis is an invasive disease caused by blood flukes, trematodes of the genus Schistosoma (S. haematobium – urogenital, S. mansoni – intestinal, S. japonicum – Japanese type).
Schistosomiasis is an invasive disease caused by blood flukes, trematodes of the genus Schistosoma (S. haematobium – urogenital, S. mansoni – intestinal, S. japonicum – Japanese type).
The blood fluke’s life cycle involves an intermediate host (aquatic mollusks), where cercariae mature. Infection occurs via consuming or contacting water with cercariae. In the definitive host, they enter the bloodstream and lymphatic system, localizing in urogenital veins, colon walls, or mesentery based on type. Upon maturity, they produce eggs, feeding on host blood alongside adults, and are excreted in feces and urine, potentially parasitizing for decades.
Indications for Schistosomiasis Testing
Given the broad clinical spectrum, initial diagnosis emphasizes history collection. In tropical regions, it’s endemic.
Many travelers to exotic countries risk Schistosoma invasion, manifesting as severe acute infection.
Identification challenges stem from numerous complications from fluke parasitism. Laboratory and instrumental methods are key.
How Schistosomiasis Diagnostics Are Conducted
Effective pathogen authentication requires a diagnostic suite:
- Epidemiological history – travel to tropical/subtropical regions.
- Clinical-laboratory analysis – fever, malaise, abdominal pain, hepatomegaly, hematuria. Complete blood count shows mild to pronounced eosinophilia (≥15%).
- Parasitological testing – detecting trematode eggs/larvae in feces and urine (urogenital form) or biopsies from bladder/rectal mucosa.
- Serological analysis – detecting specific antibodies to Schistosoma antigens in serum via ELISA, complement fixation (CF), and enzyme-labeled antibody reaction (ELAR). Intradermal allergy testing is an alternative.
- Instrumental methods – ultrasound, X-ray, or CT based on suspected parasite locations.
Result interpretation requires differentiation from atopic dermatitis, hepatitis, urethritis, pyelonephritis, acute intestinal infections, meningitis, encephalitis, pneumonia, cystitis, and bronchial asthma.
Turnaround Time for Schistosomiasis Testing
Preliminary conclusions from coprology and highly sensitive/specific (95-100%) serological reactions take 2-3 hours. Confirmation requires repeated testing and additional methods, extending the timeframe to days.
Prices and Clinics
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